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If you’re working in cannabinoid chemistry, you’ve likely heard many questions. For example, should you be using full spectrum or isolated products? What about dosage? These are all questions that are very important to know the answer to.
CBD
When someone talks about cannabinoids, they often refer to THC, the psychoactive component in marijuana. However, there are several other cannabinoids as well, such as CBD, that are not psychoactive.
CBD products like cannabichromene CBC are available in many forms, including oils, capsules, and sprays. In addition, most products come with pre-measured doses, so they’re easier to administer than tinctures. On the other hand, medicines require users to calculate the exact quantity themselves. It would help if you aimed for a dosage of around 40 milligrams per day for the best results.
There are various ways to test for THC and CBD, but the best way to ensure they are both safe and effective is to check the quality of the product. Make sure that the company uses proper extraction methods and uses third-party validation.
Isolate vs. full-spectrum products
In the CBC market, there are two types of CBD: isolate and full-spectrum. Both have their merits, but full-spectrum is likely to be more effective for a wide range of conditions. Here’s what to look for in a CBD product. First, make sure it’s clearly labeled. Second, look for a company’s lab results.
Full-spectrum products contain the total composition of the hemp plant. That means they have all cannabinoids, terpenes, and flavonoids. In addition, full-spectrum hemp flowers are processed at low temperatures, which preserves their chemical makeup. This allows them to provide the most comprehensive entourage effect, a complex synergy of different compounds.
While CBD isolate is considered the most effective for many conditions, full-spectrum CBD may be best for people sensitive to THC. However, full-spectrum CBD contains trace amounts of other cannabinoids. This can make it easier to treat certain health conditions.
Dosage
Dosage is an essential question in the development of cannabinoid compounds. In vivo studies have shown CBC to have anti-inflammatory properties. The two phytocannabinoids likely mediate this effect.
High doses of CBC may augment the THC or CBD threshold dose, thereby increasing the effect of either one. High amounts may also result in a leftward shift in the response. In addition, high-dose CBC may cause more THC to enter lipophilic tissue.
Side effects
While the benefits of cannabinoids are well documented, they may also cause adverse reactions. For instance, a person with Parkinson’s Disease may experience increased tremors while taking a high dose of cannabinoids. In these cases, doctors recommend reducing the number of cannabinoids or starting the regimen with lower doses.
Side effects of cannabinoids can range from slight impairments in psychomotor performance to permanent cognitive impairment. Although this may be a concern, patients who take cannabinoids regularly develop tolerance to the impairment of psychomotor performance. Further, some side effects may improve if the patient can overcome the symptoms.
Studies suggest that cannabinoids may effectively treat pain related to rheumatism and cancer. However, cannabinoids are still being studied in humans, and clinical trials are ongoing.
