Complementary and Alternative Medicine Market to Reach $437.9 Billion, Globally, by 2031 at 15.6% CAGR: Allied Market Research

Rise in prevalence of various chronic diseases such as cancer and cardiovascular diseases drives the growth of the global complementary and alternative medicine market.

PORTLAND, Ore., Aug. 26, 2022 /PRNewswire/ — Allied Market Research published a report, titled, Complementary and Alternative Medicine Market by Type (Medicines, Therapy), by Disease Indication (Diabetes, Cardiovascular, Neurology, Cancer, Arthritis, Others), by Distribution Channels (Direct Sales, Online Sales, Distance Correspondence): Global Opportunity Analysis and Industry Forecast, 2021–2031.” According to the report, the global complementary and alternative medicine industry generated $102.0 billion in 2021, and is estimated to reach $437.9 billion by 2031, witnessing a CAGR of 15.6% from 2022 to 2031.

Drivers, Restraints, and Opportunities

Rise in prevalence of various chronic diseases such as cancer and cardiovascular diseases and surge in popularity of complementary and alternative medicines & therapies along with rise in costs of traditional medicines and their side effects drive the growth of the global complementary and alternative medicine market. However, side effects associated with self-medication restrain the market growth. On the other hand, rise in adoption of strategies such as collaborations, mergers, and acquisitions by leading players create new opportunities in the coming years.

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Impact of Covid-19 on Complementary and Alternative Medicine Market Scenario-

  • Owing to the surge in COVID-19 infection worldwide and lack of availability of therapeutics for treatment against COVID-19, people turned toward complementary and alternative medicines as preventive measures and treatments.
  • According to the research published by Mahlagha Dehghan et. al. in January 2022, nearly 84% of the participants of the survey reported usage of one of the complementary and alternative medicines (CAMs) during the COVID-19 pandemic in Iran.
  • Adoption of yoga and meditation experienced a sharp rise during the pandemic due to closure of fitness centers, gyms, swimming pools, and sports stadiums with lockdown restrictions in place. So, people began therapies and exercising at home. This, in turn, led to the growth of the global complementary and alternative medicine market.
  • Surge in online classes and sessions that offer beginner and advanced courses related to alternative therapies such as yoga, aerobics, and meditation impacted the market positively during the pandemic.

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The medicines segment to maintain its leadership status during the forecast period

Based on type, the medicines segment accounted for the highest market share in 2021, contributing to nearly two-thirds of the global complementary and alternative medicine market, and is estimated to maintain its leadership status during the forecast period. Moreover, this segment is estimated to witness the highest CAGR of 15.9% from 2022 to 2031. This is due to surge in prevalence of chronic and autoimmune disorders and increase in the adoption of natural remedies such as Ayurvedic medicines and herbal supplements. The report also analyzes the therapy segment.

The diabetes segment to maintain its dominant share during the forecast period

Based on disease indication, the diabetes segment contributed to the largest market share in 2021, accounting

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Alternative Therapies Possible for Refractory Systematic Onset JIA, Evaluate Claims

About 1 in 7 people with systematic onset juvenile idiopathic arthritis (SJIA) will not answer to interleukin-1 or interleukin-6 inhibitors.

However targeted therapies have state-of-the-art the treatment method of systemic onset juvenile idiopathic arthritis (SJIA), a substantial range of people today with the scarce disease are refractory to the new treatment options.

In a new review article in the Annals of Drugs, investigators outlined the worries linked with these scenarios and recommended alternative procedure techniques.

Corresponding writer Susan Shenoi, MD, MS, of Seattle Children’s Clinic, and colleagues, mentioned what would make SJIA stand out from other types of juvenile idiopathic arthritis is that it has characteristics of autoinflammatory disorder.

“This has led to a paradigm change in the treatment method of patients, especially because of to the recognition of two vital cytokines in illness pathophysiology,” Shenoi and colleagues wrote.

New therapies focusing on these 2 cytokines—interleukin-1 (IL-1) and interleukin-6 (IL-6)—have led to considerable advancement in quite a few individuals, and have thus become the recommended initial-line treatment.

Continue to, the new therapies do not work for everybody. About 1 in 7 sufferers will be refractory to remedy. When there is not nonetheless an agreed-on definition for refractory SJIA, Shenoi and colleagues proposed two scenarios they say ought to constitute refractory disease. Individuals include things like sufferers who have active systemic or arthritic functions adhering to anti-IL-1 and/or anti-IL-6 remedy, or scenarios in which glucocorticoids are nonetheless expected for ailment control over and above 6 months.

“If a individual does have an satisfactory response to a single of the earlier talked about cytokine inhibitors (IL-1 or IL-6 inhibitor) the other should be applied,” Shenoi and colleagues claimed. “Refractory SJIA really should only be decided immediately after insufficient responses of each IL-1 and IL-6 blockade (although not automatically simultaneous use).”

People who in good shape the definition for refractory SJIA can be taken care of with more ailment modifying anti-rheumatic drugs (DMARDs). All those include things like typical systemic DMARDs such as thalidomide and cyclosporine, amongst many others.

Biologic DMARD possibilities incorporate tumor necrosis element-alpha inhibitors.

“In standard TNF-α inhibitors are significantly less productive for the systemic capabilities of the disease but may possibly help with arthritic features of SJIA,” the authors stated.

Rituximab (Rituxan) and abatacept (Orencia) are other biologics that can be utilized for refractory individuals, they mentioned.

Lastly, Shenoi and colleagues said patients refractory to IL-1 and IL-6 inhibitors can also be dealt with with qualified synthetic DMARDs like Janus kinase inhibitors or other immunomodulatory inhibitors.

However, the investigators additional that some patients will have extreme issues, these types of as macrophage activation syndrome (MAS) and interstitial lung ailment (ILD), which can be lifetime-threatening.

For MAS, treatment method solutions contain emapalumab (Gamifant), a monoclonal antibody that binds interferon-γ, and anti-thymocyte globulin. For ILD, mycophenolate mofetil (CellCept), cyclosporine, and Janus kinase inhibitors may possibly be acceptable options.

Shenoi and colleagues stated patients with ILD pose a substantial new obstacle, as patients who acquire serious lung illness have a mortality

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The Impact of Complementary and Alternative Medicine on Insomnia: A Systematic Review

Insomnia is identified by difficulty in maintaining sleep and early morning awakenings [1]. Consequently, it further causes workplace absenteeism, accidents, and a decline in productivity which imparts tremendous societal and economic impact [2]. One-third of the general population encounter insomnia symptoms across their lifespan [3]. Insomnia should not be confused with sleep deprivation, the former being the inability to sleep adequately, either in length or quality [4]. Most studies suggested predominance rates of insomnia disorder from 5% to 15% [5-7]. Insomnia could be a persistent issue in 31% to 75% of patients, with more than two-thirds revealing side effects for at least one year [6-8]. Due to the increasing work pressure and social challenges in an advanced society, most of the masses cannot get adequate sleep and suffer from sleep disturbance [9-12]. A detailed study shows that around 30% of adults suffer from sleep disturbance [7]. It mainly affects females and is increasing with advancing age [8]. Insomnia may be acute or chronic, and primary or secondary [1]. Primary insomnia can be defined as an individual experiencing a sleep disorder due to stress or emotions, while secondary insomnia can be due to co-morbid conditions or prior illness [1]. Insomnia has been associated with many comorbidities such as hypertension, cardiovascular disease, depression, obesity, and diabetes [2]. It can also lead to alterations in attention with episodic memory, and these cognitive impairments are clinically significant [1,2]. Hence, to maintain an individual’s overall health, the treatment of insomnia is necessary [9, 10]. Conventional methods of treating insomnia generally involve either pharmacotherapies or psychological interventions [11]. The use of such kinds of drugs can cause serious adverse effects such as cognitive impairment, oversedation, daytime drowsiness, rebound discontinuation, and psychomotor disturbance [12]. In recent years, benzodiazepines (diazepam and related drugs) or nonbenzodiazepine hypnotics (zolpidem or zopiclone} have been chosen over older barbiturates which can cause death in cases of overdose. In older patients, sedating antipsychotics, e.g., olanzapine or quetiapine, and sedating anti-depressants with older tricyclic drugs, are generally regarded as “off label” [11, 12]. The new treatment guidelines evolved for benzodiazepine include low doses of sedating antipsychotics, antidepressants, and mood stabilizers [11]. Although pharmacotherapies and psychological interventions remain essential for conventional treatment, due to various motivational factors, interest in using alternative therapies and products for insomnia has developed over the last two decades.

One common treatment group used by patients with insomnia is complementary and alternative medicine (CAM) [5-7]. Research on adult insomnia patients has found that 4.5% of them practised CAM to treat their condition [9]. CAM use can be seen extensively among patients with mental disorders, commonly for managing depression or insomnia. CAM generally includes extensive therapies based on different geographical regions from various schools of thought [8]. Common CAM therapies for insomnia include herbal and nutritional medicine, acupuncture, acupressure, yoga, tai chi, and mind-body practices [10]. Mind-body interventions such as

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Alternative Treatments for Multiple Sclerosis (MS)

Multiple sclerosis, or MS, is an autoimmune disease in which the immune system attacks the protective covering of nerve cells (myelin) in the brain and spinal cord, impairing nerve signaling and causing a variety of symptoms.

This is a lifelong condition, but there are a variety of ways people with MS can prevent the disease from progressing, and treat or cope with symptoms.

This article discusses complementary and alternative medicine treatment options for MS.

ZenShui / Milena Boniek / Getty Images


Alternative vs. Complementary Therapies

Alternative therapies are treatment options that are used instead of modern medical options, while a complementary therapy is a treatment option used in conjunction with modern medicine. The same treatments can be used as either alternative or complementary therapies.

Alternative Treatments

A number of complementary or alternative therapies can be used to help treat multiple sclerosis, including exercise, diet, acupuncture and other natural treatments.

Exercise

Exercise is recommended for people with MS as it has been shown to improve symptoms and help with mental and physical health. Adapted options are available for people who have physical disabilities.

Exercise may also help change the course of the disease by slowing its progression, but more research is needed.

Physical activity options for people with MS depend on ability and preference, and may include:

  • Aerobic exercise
  • Strength training
  • Swimming or water exercise
  • Walking
  • Hobbies that involve movement
  • Stair climbing
  • Gardening, cooking, and household chores
  • Yoga, Pilates, tai chi

Diet

People with MS are advised to eat a nutritious, well-balanced diet to help manage symptoms and improve overall health and well-being. Nutrition may play a role in slowing the progression of MS, but more research is needed.

Some nutrition recommendations to help manage MS include:

  • Eat plenty of vegetables, fruits, and legumes (beans, lentils, peas, and peanuts).
  • Limit salt, animal fat, fried foods, and sugar.
  • Focus on lower-calorie foods.
  • Avoid overeating.

Massage

It is unclear if massage therapy improves MS, but there is research to support limited benefits without harm.

Massage may help people with symptoms such as:

Acupuncture

Acupuncture is the use of needles inserted into the skin to stimulate different places on the body called “acupoints,” or acupressure points. This treatment may help to reduce symptoms of MS, but there is limited research to show its effectiveness.

Some MS symptoms that acupuncture may improve include:

Medical Marijuana

Medical marijuana (cannabis) may help reduce specific symptoms caused by MS. It may improve MS symptoms such as:

  • Spasticity: Extreme muscle stiffness or tightness
  • Pain: Reduced pain related to spasticity
  • Bladder challenges: Decreased need to urinate

As with any treatment option, the potential benefits must be considered along with the possible side effects. It is important to work with a healthcare professional when considering cannabis for MS treatment and to seek help if experiencing any side effects, especially and changes in mental health.

If you are having suicidal thoughts, contact the 988 Suicide & Crisis LIfeline at 800-273-8255–or text 988–for support and assistance from a trained

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New product has the potential to provide an alternative to opioids and other hugely addictive medicine — ScienceDaily

A Northwestern University-led workforce of researchers has developed a smaller, delicate, adaptable implant that relieves soreness on demand and with out the use of medicine. The initially-of-its-kind device could offer a considerably-required substitute to opioids and other really addictive drugs.

The biocompatible, h2o-soluble system will work by softly wrapping all around nerves to produce precise, targeted cooling, which numbs nerves and blocks pain indicators to the mind. An exterior pump permits the person to remotely activate the unit and then maximize or lessen its depth. Soon after the system is no for a longer period desired, it normally absorbs into the human body — bypassing the require for surgical extraction.

The researchers think the device has the likely to be most useful for patients who bear regime surgical procedures or even amputations that typically demand put up-operative medicines. Surgeons could implant the gadget for the duration of the process to enable handle the patient’s article-operative agony.

The research will be printed in the July 1 concern of the journal Science. The paper describes the device’s design and demonstrates its efficacy in an animal design.

“Though opioids are extremely effective, they also are really addictive,” said Northwestern’s John A. Rogers, who led the device’s development. “As engineers, we are motivated by the plan of treating discomfort with out medicine — in approaches that can be turned on and off right away, with user command in excess of the depth of reduction. The engineering noted below exploits mechanisms that have some similarities to all those that bring about your fingers to really feel numb when cold. Our implant lets that outcome to be produced in a programmable way, immediately and domestically to targeted nerves, even these deep inside of surrounding tender tissues.”

A bioelectronics pioneer, Rogers is the Louis Simpson and Kimberly Querrey Professor of Elements Science and Engineering, Biomedical Engineering and Neurological Surgical procedure in the McCormick School of Engineeringand Northwestern College Feinberg Faculty of Medication. He also is the founding director of the Querrey Simpson Institute for Bioelectronics. Jonathan Reeder, a previous Ph.D. candidate in Rogers’ laboratory, is the paper’s to start with creator.

How it works

Though the new gadget might sound like science fiction, it leverages a very simple, common concept that anyone is aware: evaporation. Related to how evaporating sweat cools the overall body, the gadget incorporates a liquid coolant that is induced to evaporate at the certain locale of a sensory nerve.

“As you interesting down a nerve, the signals that vacation by means of the nerve turn out to be slower and slower — ultimately halting totally,” mentioned research coauthor Dr. Matthew MacEwan of Washington College University of Medication in St. Louis. “We are specially focusing on peripheral nerves, which connect your mind and your spinal wire to the relaxation of your body. These are the nerves that talk sensory stimuli, like pain. By offering a cooling impact to just a single or two specific nerves, we can effectively modulate suffering alerts in a

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