Use of Frozen Embryos Tied to Greater Odds for Hazardous Complication of Pregnancy

By By Dennis Thompson HealthDay Reporter, HealthDay Reporter

(HealthDay)

MONDAY, Sept. 26, 2022 (HealthDay Information) — Frozen embryos surface to be linked with a drastically better hazard of dangerously significant blood force for the woman in pregnancies realized via in vitro fertilization, a important new research reports.

Expectant moms had been 74% more possible to build superior blood tension if her pregnancy resulted from a frozen embryo, as opposed to a clean embryo or normal conception, according to investigation of far more than 4.5 million pregnancies.

These success could mark a sea transform in the way assisted copy is performed, scientists reported.

“Frozen embryo transfers are now more and more frequent all around the environment, and in the previous several yrs, some medical professionals have started skipping contemporary embryo transfer to routinely freeze all embryos in their medical follow, the so-referred to as ‘freeze-all’ tactic,” said direct researcher Dr. Sindre Petersen, a doctoral fellow at the Norwegian College of Science and Technological know-how in Trondheim.

“Our final results spotlight that careful consideration of all positive aspects and opportunity challenges is wanted prior to freezing all embryos as a schedule in clinical practice,” he added. “A comprehensive, individualized dialogue amongst medical professionals and clients about the gains and risks of a fresh new vs. frozen embryo transfer is vital.”

For the research, posted Sept. 26 in Hypertension, a journal of the American Coronary heart Association, the researchers reviewed the professional medical data of nearly 2.4 million women from Denmark, Norway and Sweden who had one or a lot more solitary deliveries involving 1988 and 2015. The females ranged in age from 20 to 44.

Of the a lot more than 4.5 million pregnancies determined, 4.4 million were being the natural way conceived. Far more than 78,000 concerned clean embryo transfers, whilst far more than 18,000 included frozen embryos.

Substantial blood force for the duration of pregnancy often indicators preeclampsia, a complication that can endanger equally the mom and the fetus. Preeclampsia affects about 1 in each individual 25 U.S. pregnancies, in accordance to the American Heart Association.

They specially zeroed in on 33,000 pregnancies in which a girl experienced conceived by a lot more than one particular technique, which permitted the workforce to evaluate siblings.

Scientists found a woman’s hazard of a large blood force ailment doubled when she been given a frozen embryo for the duration of IVF, compared to when the identical female conceived a sibling naturally.

Risk was no larger with the use of new embryos when compared to natural conception in females who acquired expecting the two approaches.

“Our sibling comparisons point out that the larger threat is not brought about by factors associated to the mom and dad, rather, however, that some IVF procedure elements may perhaps be associated,” Petersen explained in a journal news launch. “Potential research must examine which components of the frozen embryo transfer procedure could affect chance of hypertension throughout being pregnant.”

Resource: American Heart Affiliation, news release, Sept. 26,

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How Texas abortion law turned a pregnancy loss into a medical trauma : Shots

Elizabeth and James Weller at their home in Houston two months after losing their baby girl due to a premature rupture of membranes. Elizabeth could not receive the medical care she needed until several days later because of a Texas law that banned abortion after six weeks.

Julia Robinson for NPR


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Elizabeth and James Weller at their home in Houston two months after losing their baby girl due to a premature rupture of membranes. Elizabeth could not receive the medical care she needed until several days later because of a Texas law that banned abortion after six weeks.

Julia Robinson for NPR

New, untested abortion bans have made doctors unsure about treating some pregnancy complications, which has led to life-threatening delays and trapped families in a limbo of grief and helplessness.

Elizabeth Weller never dreamed that her own hopes for a child would become ensnared in the web of Texas abortion law.

She and her husband began trying in late 2021. They had bought a house in Kingwood, a lakeside development in Houston. Elizabeth was in graduate school for political science, and James taught middle-school math.

The Wellers were pleasantly surprised when they got pregnant early in 2022.

In retrospect, Elizabeth says their initial joy felt a little naive: “If it was so easy for us to get pregnant, then to us it was almost like a sign that this pregnancy was going to be easy for us.”

Things did go fairly smooth at first. Seventeen weeks into the pregnancy, they learned they were expecting a girl. They also had an anatomy scan, which revealed no problems. Even if it had, the Wellers were determined to proceed.

“We skipped over the genetic testing offered in the first trimester,” Elizabeth says. “I was born with a physical disability. If she had any physical ailments, I would never abort her for that issue.”

Elizabeth thought of abortion rights in broad terms: “I have said throughout my life I believe that women should have the access to the right to an abortion. I personally would never get one.”

And at this particular point in her life, pregnant for the first time at age 26, it was still somewhat abstract: “I had not been put in a position to where I had to weigh the real nuances that went into this situation. I had not been put in the crossroads of this issue.”

But in early May, not long after the uneventful anatomy scan, the Wellers suddenly arrived at that crossroads. There they found themselves pinned down, clinically and emotionally, victims of a collision between standard obstetrical practice and the rigid new demands of Texas law.

It was May 10, 2022. Elizabeth was 18 weeks pregnant. She ate a healthy breakfast, went for a walk outside and came back home.

In the nursery upstairs, they had already stashed some baby clothes and new cans of paint. Down in the kitchen, images from recent scans and ultrasounds

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Why Are More Women Using Pot, Other Cannabis Goods During Pregnancy? | Well being News

By Amy Norton HealthDay Reporter

(HealthDay)

MONDAY, Dec. 20, 2021 (HealthDay News) — A increasing variety of expecting women of all ages are utilizing marijuana or other hashish goods, and a new review indicates that relief of indications this kind of as early morning sickness might be a primary cause.

In the latest several years, scientific tests have documented a rise in cannabis use all through being pregnant. A person U.S. governing administration study discovered that involving 2002 and 2017, the number of pregnant gals who said they’d utilized marijuana in the past thirty day period doubled — from about 3.5% to 7%.

But the factors they choose to use marijuana have not been apparent.

So for the new examine, scientists did in-depth interviews with 52 pregnant or breastfeeding folks who experienced utilized different hashish merchandise just before pregnancy — not only smoked cannabis, but other products and solutions like edibles.

Of that team, 30 ongoing to use cannabis after getting to be expecting. And practically all explained it was to support regulate signs, most frequently morning sickness.

That is an critical place for obstetricians and other health and fitness care vendors to know, claimed direct researcher Meredith Vanstone of McMaster University in Hamilton, Ontario, Canada.

“I do get worried that companies frequently assume that these are folks who just will not treatment — that they are making use of hashish for entertaining and could stop if they required,” Vanstone mentioned.

“That is not what we uncovered,” she mentioned.

In common, the review participants were being well-educated on the proof, or absence of it, and produced a deliberate alternative on no matter whether to continue on using cannabis all through being pregnant, Vanstone famous.

That is not to say that cannabis is a good solution for controlling early morning sickness.

Significantly of that has to do with the unknowns, the teams say. Some studies have linked mothers’ marijuana use throughout pregnancy to an increased danger of preterm delivery, low delivery fat, and understanding and interest difficulties in their kids.

People studies do not establish marijuana is to blame — in element mainly because it is challenging to individual any results of marijuana from cigarette smoking cigarettes and ingesting, which usually go together.

And significantly fewer is regarded about other hashish merchandise that have grow to be well-liked in latest several years, like edibles and cannabidiol (CBD), mentioned Christina Chambers, a professor at the University of California, San Diego.

Now that cannabis is legal in several U.S. states, there is renewed interest in the possible results of prenatal use, stated Chambers, who is also system director of MotherToBaby California.

MotherToBaby is a nonprofit that gives science-based mostly details on the security of remedies and other exposures through being pregnant.

“We have to have additional research,” Chambers mentioned. “The very best tips we have now, in the absence of substantial-quality information, is to keep away from (utilizing cannabis) all through being pregnant and breastfeeding.”

When it arrives to breastfeeding

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